منابع مشابه
Laying Futility to Rest
In this essay I examine the formal structure of the concept of futility, enabling identification of the appropriate roles played by patient, professional, and society. I argue that the concept of futility does not justify unilateral decisions to forego life-sustaining medical treatment over patient or legitimate surrogate objection, even when futility is determined by a process or subject to et...
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The lack of data authentication and integrity guarantees in the Domain Name System (DNS) facilitates a wide variety of malicious activity on the Internet today. DNSSec, a set of cryptographic extensions to DNS, has been proposed to address these threats. While DNSSec does provide certain security guarantees, here we argue that it does not provide what users really need, namely end-to-end authen...
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Modern systems-on-chip (SoCs) incorporate a large and growing number of specialized hardware units that must be integrated into a unified address space via a shared bus topology. This process is labor-intensive and error-prone because the interface requirements of all connected blocks must bemutually satisfied. The design productivity gains derived from the modularity of RISC-V are bottlenecked...
متن کاملThe utility of futility.
See related article, pages 2410–2414. In this issue, Palesch et al 1 discuss the single-arm, phase II futility study design and illustrate how its use might have avoided 3 large (and costly) but negative phase III therapeutic trials for ischemic stroke patients. The authors offer strong arguments to support their conclusion that use of this design as a strategy in phase II development “could pe...
متن کاملFibonacci and Futility
The present paper deals with statements of a recently published book of the “Nauka” Publishing House (Moscow, 2005) on regularity of appearance of the Fibonacci golden mean as a quantitative characteristic in the social and economical sphere and necessity to follow it under increasing management efficiency. The present paper proposes a negative answer to the question on necessity of following t...
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ژورنال
عنوان ژورنال: Hispanic American Historical Review
سال: 1930
ISSN: 0018-2168,1527-1900
DOI: 10.1215/00182168-10.3.265